3-Methylphenyl 5-chloro-2-(ethylsulfonyl)-4-pyrimidinecarboxylate
SBI-115
CAS: 882366-16-7
Molecular Formula: C14H13ClN2O4S
3-Methylphenyl 5-chloro-2-(ethylsulfonyl)-4-pyrimidinecarboxylate - Names and Identifiers
3-Methylphenyl 5-chloro-2-(ethylsulfonyl)-4-pyrimidinecarboxylate - Physico-chemical Properties
| Molecular Formula | C14H13ClN2O4S |
| Molar Mass | 340.78 |
| Solubility | DMSO : 150 mg/mL (Need ultrasonic);H2O : < 0.1 mg/mL (insoluble) |
| Storage Condition | 2-8°C |
3-Methylphenyl 5-chloro-2-(ethylsulfonyl)-4-pyrimidinecarboxylate - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.934 ml | 14.672 ml | 29.344 ml |
| 5 mM | 0.587 ml | 2.934 ml | 5.869 ml |
| 10 mM | 0.293 ml | 1.467 ml | 2.934 ml |
| 5 mM | 0.059 ml | 0.293 ml | 0.587 ml |
Last Update：2024-01-02 23:10:35
3-Methylphenyl 5-chloro-2-(ethylsulfonyl)-4-pyrimidinecarboxylate - Reference Information
| biological activity | SBI-115 is a novel antagonist of TGR5 (GPCR19). SBI-115 in Cystic bile duct cells can inhibit cell proliferation, reduce the growth rate of bile duct cells and the level of cAMP. |
| Target | Value |
| Cell Line: | shRNA-transfected ADPKD cholangiocytes |
| Concentration: | 100, 200 µM |
| Incubation Time: | 24 hours |
| Result: | Inhibited proliferation (by 32-48%) triggered by pre-treatment of cystic cholangiocytes with TLCA. |
Last Update：2024-04-10 22:29:15
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Spot supply
Product Name: SBI-115 Visit Supplier Webpage Request for quotationCAS: 882366-16-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
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